It's the Team, Not the Beam

At the conclusion of a recent office visit, one of our patients summarized his feelings and stated, with a sense of absolute conviction, “The only type of radiation therapy I am willing to undergo is proton therapy.” In contrast, another recent patient facing a similar situation stated, “I don't care which I get [proton or photon therapy]; to me, it sounds like it's the team, not the beam.” The former patient put his hope in a technology; the latter patient prioritized the experience of his care team over any particular technology.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Payment Policy Source Type: research

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o T, Khan R Abstract Radiochromic films have been widely studied for clinical dosimetry in conventional external beam radiation therapy. With an increase in practice of proton therapy, such films are being conveniently used; however, their spectroscopic characterization for this modality is lacking. This work investigated the response of the EBT3 radiochromic films irradiated in a Mevion S250™ clinical proton beam. Dose, dose rate, inter-batch, sensitivity, and linear energy transfer (LET) dependencies of the films were studied. Pieces of the radiochromic films from different batches were irradiated using a ...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research
This study was performed to determine the clinical and patient-reported outcomes for patients with PC treated with HFPT.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research
PMID: 31166085 [PubMed - as supplied by publisher]
Source: Journal of Applied Clinical Medical Physics - Category: Physics Authors: Tags: J Appl Clin Med Phys Source Type: research
It is critical that rigorous evaluation of technology in radiation oncology be undertaken during the early stages of implementation or when there is a marked cost differential. Prospective clinical data proving the clinical effectiveness of emerging technology may not be available to guide proper investment and development. In these scenarios, models can be used to simulate expected clinical outcomes and predict comparative effectiveness and cost-effectiveness.1 In this edition of the Red Journal, 2 studies use model-based approaches to compare photon intensity modulated radiation therapy (IMRT) to proton beam therapy (PBT...
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Clinical Investigation Source Type: research
Publication date: Available online 22 May 2019Source: Practical Radiation OncologyAuthor(s): Ashlyn S. Everett, Bradford S. Hoppe, Debbie Louis, Andrew M. McDonald, Christopher M. Morris, Nancy P. Mendenhall, Zuofeng Li, Stella FlampouriAbstractIntroductionPatients with lower mediastinal lymphoma (LML) benefit dosimetrically from proton therapy (PT) compared with intensity-modulated radiotherapy (IMRT). The added dosimetric benefit of deep-inspiration breath-hold (DIBH) is unknown; therefore, we evaluated IMRT versus PT and free-breathing (FB) versus DIBH among patients with LML.Materials and MethodsTwenty-one patients wit...
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
(Washington University School of Medicine) Proton therapy results in fewer side effects than traditional X-ray radiation therapy for many cancer patients, according to a new study led by Washington University School of Medicine in St. Louis and the Perelman School of Medicine at University of Pennsylvania. Even with reduced side effects, proton therapy resulted in cure rates similar to those of X-ray radiation therapy.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
(University of Pennsylvania School of Medicine) Cancer patients getting proton therapy instead of traditional photon radiation are at a significantly lower risk of experiencing side-effects from their radiation therapy, while cure rates are almost identical between the two groups.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Conclusion We observed a significant increase in global lung inflammation bilaterally as measured by quantification of PG. However, no significant change in global lung inflammation was noted after proton therapy. Future larger studies are needed to determine whether this difference correlates with lower risks of radiation pneumonitis in NSCLC patients treated with proton therapy.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: ORIGINAL ARTICLES Source Type: research
1139Introduction: Thoracic malignancies are among the most common malignancies diagnosed both in the United States and worldwide. Radiation therapy (RT) plays an important role in the treatment of thoracic malignancies. Depending on the primary disease site and tumor stage, RT can be used as monotherapy, or as part of multimodality therapy for curative intent, or for palliative reduction of advanced disease. In fact, more than 50% of all patients with thoracic malignancies will receive RT as part of their multidisciplinary care. 18F-Fluorodeoxyglucose positron emission tomography (PET) is commonly used for initial cancer d...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Educational Exhibit Posters Source Type: research
Abstract The purpose of this study was the evaluation of the impact of a variable relative biological effectiveness (RBE) compared to a constant RBE value of 1.1 in proton therapy prostate trials due to uncertainties in α/β ratio.
 
 Twenty patients receiving passive scattered proton therapy (PSPT) and fifteen patients receiving intensity modulated proton therapy (IMPT) were compared to twenty patients treated with 7-field intensity modulated photon therapy (IMRT). For proton beam therapy (PBT), the RBE was estimated using two different RBE models. Tumor control probabilities (TCP) and n...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research
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