New dad celebrates first father's day after a brain tumor left him infertile

Derin Gebhardt, 37, from Roundup, Montana, was diagnosed in May 2017 with a pituitary tumor, which was causing a decrease in normal levels of sex hormones and behind his infertility.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Condition:   Glioma Interventions:   Diagnostic Test: Intra-operative imaging of 5-ALA fluorescence using ultra-high sensitivity camera;   Diagnostic Test: Intra-operative imaging of 5-ALA fluorescence using in-built operative microscope camera;   Diagnostic Test: Biopsies Sponsors:   University of Oxford;   Oxford University Hospitals NHS Trust Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
 Many infertile couples automatically assume that if they can't get pregnant on their own, they're going to require medical attention , and seek out a gynecologist for assistance.While this is true for many couples, there are also lots of others who can solve the problem for themselves in the bedroom using simple medical tools, especially when the problem is a mechanical one  of their being unable to deposit the semen in the vagina.Part of the of the problem is most doctors will not explain this simpler option to them , because treating patients is their only source of income, and they can't afford to give away t...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
 While it's reassuring to remember that in case your infertility is due to a medical problem, you can always go to a doctor to seek medical help , the fact still remains that going to a doctor is an expensive exercise.You need to pay the consultation fees; you need to pay for the medicines; you need to pay for the scans and the treatment; and you need to take time away from work and make excuses for being absent.Also, doctor ’s clinics can be scary and intimidating. They poke and prod you; force you to assume highly undignified positions; disregard your privacy; and every time you go, there is a new strange...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
Publication date: October 2020Source: Journal of Clinical Neuroscience, Volume 80Author(s): Guo-Bin Zhang, Hua-Wei Huang, Hao-Yi Li, Xiao-Kang Zhang, Yong-Gang Wang, Song Lin
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Condition:   Glioma Interventions:   Diagnostic Test: Intra-operative imaging of 5-ALA fluorescence using ultra-high sensitivity camera;   Diagnostic Test: Intra-operative imaging of 5-ALA fluorescence using in-built operative microscope camera;   Diagnostic Test: Biopsies Sponsors:   University of Oxford;   Oxford University Hospitals NHS Trust Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 10 September 2020Source: Seminars in Cancer BiologyAuthor(s): Yang Zhang, Ying Xiao, Gui-Chen Li, Feng-Yan Gong, Xiao-Na Zhang, Kun Hou
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
One of the problems of being infertile because of erectile dysfunction ( impotence) is that these men can ’t stop thinking of themselves as failures . They can't even do such a simple thing like making a baby in their bedroom - something which millions of men have been doing since time immemorial !The problem is compounded by the fact that their wife will often blame herself. She will feel that her husband does not find her sexually attractive, which is why he is not able to get an erection when have sex with her.This can be hard to come to terms with - specially for many young successful professional men w...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
One of the problems of being infertile because ofvaginismusis that women can ’t stop thinking of themselves as failures . They can't even do such a simple thing like making a baby in their bedroom - something which millions of women have been doing since time immemorial !This can be hard to come to terms with - specially for many young successful professional career women who are so used to getting everything they want in life. They are smart; they do well in exams; they get the job which they want ; and marry the husband they want to. Then when they find that they can't get a baby, their self-esteem takes a big toss...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
In the present study, to delve into the effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) combined with temozolomide (TMZ) on high-grade glioma cells and related mechanism, six cases of high-grade glioma cells from patient’s tumor tissues were cultured. 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di- phenytetrazoliumromide 3-(4,5)-dimethylthiahiazo (-z-y1)-3,5-di- phenytetrazoliumromide (MTT) assay was performed to detect cell proliferation and toxicity. Flow cytometry was performed to ascertain cell cycle and apoptosis rate. To detect the expressions of O6-methylguanine-DNA methyltransferase (MGMT) methy...
Source: Anti-Cancer Drugs - Category: Cancer & Oncology Tags: Preclinical Reports Source Type: research
We describe a 42-year-old man with chronic kidney disease stage 4 who was diagnosed with a mediastinal germ cell tumor and metastases in lung and brain. Treatment with cisplatin-etoposide was considered essential for a chance of cure. In order to administer the full cisplatin dose, 4-hour hemodialysis sessions were performed after each cisplatin infusion. During treatment cycle 3, 4 and 5, total and unbound plasma platinum concentrations were measured. Trough concentrations and half-life were at the higher end of the range of those observed in patients with adequate renal function who received the same dose of cisplatin. H...
Source: Anti-Cancer Drugs - Category: Cancer & Oncology Tags: Case Reports Source Type: research
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