Authors' Response

We appreciate the response of Clark et  al. to our article, Challenges in Recruiting Patients to a Controlled Feasibility Study of a Drug for Opioid-Induced Constipation: Lessons From the Population With Advanced Cancer (JPSM 2019;57(5):e5-e8), and their extensive experience from the Australian Palliative Care Outcomes Collaboration. A lthough we agree that distress from constipation may be limited to a small percentage of the cancer population and contribute to recruitment challenges, other factors we encountered included late referrals, rapid trajectory of disease, limited opioid use, and disinterest because of dealing with mult iple issues during advanced illness.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Tags: Letter Source Type: research