Synergistic Palladium/Enamine Catalysis for Asymmetric Hydrocarbon Functionalization of Unactivated Alkenes with Ketones

Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB01165J, PaperChiyu Wei, Xiaohan Ye, Qingyu Xing, Yong Hu, Yan Xie, Xiaodong Shi Synergistic palladium and enamine catalysis were explored to promote ketone addition to unactivated olefin. Secondary amine-based organocatalyst was identified as the optimal co-catalyst for the directed Pd-catalyzed alkene activation. Furthermore,... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research