A new method to support the cross-reactivity in allergenic reactions of cypress and wheat using piezoelectric signals

Publication date: July 2019Source: Materials Science and Engineering: B, Volume 246Author(s): Francisco Quintanilla, Susana Vargas, Domingo Rangel, Ulises Merino, Rogelio RodríguezAbstractA novel method is proposed to determine whether two proteins from different sources can be, potentially, candidates for cross-reactions allergies. The cross-reaction allergies are usually based on the similarity, partial or total, of the amino acids sequences of both proteins; however, according to our results, the recognition between proteins from different sources is carried out at secondary structure level; at this level the local shape and the charge distribution, of these proteins have to be similar to share cross-reactions. The charge distribution controls, to some extent, the ionic transport in the electrolyte. The ionic transport in cypress and wheat samples was determined and compared each other, obtaining that the piezoelectric relaxation voltages were practically the same. Several samples from cupressus arizonica Cup a 1 and the triticum aestivum gli mRNA and triticum aestivum clone 175 glutenin (GluB3-2) mRNA were prepared.
Source: Materials Science and Engineering: B - Category: Materials Science Source Type: research