Irritable Bowel Syndrome and Control Volunteers: Diet Challenge

Condition:   IBS - Irritable Bowel Syndrome Intervention:   Sponsors:   Indiana University;   National Institutes of Health (NIH) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Publication date: Available online 18 July 2019Source: Best Practice &Research Clinical GastroenterologyAuthor(s): Per M. Hellström, Peter BennoAbstractFunctional gastrointestinal disorders are the most common disorders encountered in the clinical gastroenterology setting. Over the years the Rome process has generated consensus definitions of functional gastrointestinal disorders, and given diagnostic criteria, based on various symptom patterns, that have evolved over the years. The latest Rome IV consensus was presented in May, 2016. This summary points out some of the important changes made from the Rome III 200...
Source: Best Practice and Research Clinical Gastroenterology - Category: Gastroenterology Source Type: research
Sulphate-reducing bacteria (SRB) are studied across a range of scientific fields due to their characteristic ability to metabolise sulphate and produce hydrogen sulphide, which can lead to important consequences for human activities. Importantly, they are members of the human gastrointestinal microbial population, contributing to the metabolism of dietary and host secreted molecules found in this environment. The role of the microbiota in host digestion is well studied, but the full role of SRB in this process has not been established. Moreover, from a human health perspective, SRB have been implicated in a number of funct...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
This study provides an overview of the alterations of microbiota and may aid in identifying potential 16S rRNA gene amplicons mucosal biomarkers for IBD and IBS.
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
The FDA has authorized marketing of the first medical device for adolescents with abdominal pain associated with irritable bowel syndrome (IBS). The device, which is available by prescription only, is indicated for patients aged 11 through 18 years.
Source: JAMA - Category: General Medicine Source Type: research
There is controversy about whether psychological factors (anxiety and depression) increase seeking of healthcare by patients with irritable bowel syndrome (IBS). We investigated whether psychological factors increase healthcare seeking by patients with IBS and the effects of extra-GI symptoms.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: AGA Section Source Type: research
AbstractTo investigate long-term health sequelae of cryptosporidiosis, with especial reference to post-infectious irritable bowel syndrome (PI-IBS). A prospective cohort study was carried out. All patients with laboratory-confirmed, genotyped cryptosporidiosis in Wales, UK, aged between 6  months and 45 years of age, over a 2-year period were contacted. Five hundred and five patients agreed to participate and were asked to complete questionnaires (paper or online) at baseline, 3 and 12 months after diagnosis. The presence/absence of IBS was established using the Rome III criteria for different age groups. Tw...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
We report the chemical synthesis of this physiologically important oxysterol beginning with cholesterol. The key feature of this synthesis involves a regioselective C3-allylic oxidation of a 3-desoxy-Δ4-7α-formate steroid precursor to form 7α-formyloxy-cholest-4-en-3-one, which was saponified to yield 7α-hydroxy-cholest-4-en-3-one.Graphical abstract
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
Publication date: October 2019Source: Biomedicine &Pharmacotherapy, Volume 118Author(s): Qiuke Hou, Shuilian Zhu, Changrong Zhang, Yongquan Huang, Yajuan Guo, Peiwu Li, Xinlin Chen, Yi Wen, Quanbin Han, Fengbin LiuAbstractTo investigate effects of berberine exerts on A20 expression and regulation of intestinal epithelial tight junctions via the TNF-α-NF-κB-MLCK pathway in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D).C57BL/6 wild type (WT) and A20 IEC-KO mice (48 each) were randomly divided into normal control (NC), model control (MC), rifaximin and berberine groups (12 mice per group). An experimen...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Conditions:   Non-celiac Gluten Sensitivity;   Irritable Bowel Syndrome Interventions:   Dietary Supplement: diet containing gluten;   Dietary Supplement: Placebo Sponsor:   University of Bari Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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