Genetic and Inflammatory Biomarkers Classify Small Intestine Inflammation in Asymptomatic First-degree Relatives of Patients With Crohn ’s Disease

Relatives of individuals with Crohn's disease (CD) carry CD-associated genetic variants and are often exposed to environmental factors that increase their risk for this disease. We aimed to estimate the utility of genotype, smoking status, family history, and other biomarkers can be used to calculate risk in asymptomatic first-degree relatives of patients with CD.

Source: Clinical Gastroenterology and Hepatology - June 12, 2019 Category: Gastroenterology Authors: Kirstin M. Taylor, Ken B. Hanscombe, Natalie J. Prescott, Raquel Iniesta, Matthew Traylor, Nicola S. Taylor, Steven Fong, Nicholas Powell, Peter M. Irving, Simon H. Anderson, Christopher G. Mathew, Cathryn M. Lewis, Jeremy D. Sanderson Source Type: research