Neuropsychiatric Symptoms as Risk Factors for Cognitive Decline in Clinically Normal Older Adults: The Cache County Study.

CONCLUSION: In conclusion, among clinically normal older adults derived from this population-based study, total burden of NPS was associated with longitudinal cognitive decline. These results add to the evidence that NPS are risk factors for or clinical indicators of preclinical dementia syndrome. Our study was an exploratory study and we did not control for multiple comparisons. PMID: 31186157 [PubMed - as supplied by publisher]
Source: The American Journal of Geriatric Psychiatry - Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research

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AbstractBackgroundPeople with Alzheimer's disease (AD) often have multimorbidity and take multiple medicines. Yet few studies have examined medicine utilization for comorbidities comparing people with and without AD.ObjectiveThe aim was to investigate the patterns of medication use for comorbidities in people with and without AD.MethodsAn Australian population ‐based study was conducted using the Pharmaceutical Benefits Scheme 10% sample of pharmacy claims data.People with ADwere defined as those dispensed medicines for dementia (cholinesterase inhibitors, memantine, or risperidone for behavioral and psychological sympto...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: Original Research Article Source Type: research
OBJECTIVE: To examine the association between hearing aids (HAs) and time to diagnosis of Alzheimer disease (AD) or dementia, anxiety or depression, and injurious falls among adults, aged 66 years and older, within 3 years of hearing loss (HL) diagnosis. ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
FRIDAY, Sept. 6, 2019 -- Use of hearing aids is associated with lower risks for being diagnosed with Alzheimer disease, dementia, depression, anxiety, and injurious falls among elderly adults diagnosed with hearing loss, according to a study...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Older adults who use hearing aids may be less likely to develop depression, anxiety, and dementia for at least three years after a hearing loss diagnosis compared with those who do not begin using hearing aids, according to astudy published Wednesday in theJournal of the American Geriatrics Society. In addition, these individuals appear less likely to get injured in a fall.“By providing enhanced hearing input, HAs [hearing aids] may facilitate greater social engagement, lower levels of effort to recognize sounds and speech, lower levels of depression or anxiety symptoms, higher levels of physical balance, and greater...
Source: Psychiatr News - Category: Psychiatry Tags: Alzheimer's anxiety dementia depression fall injury geriatric psychiatry health insurance hearing aid hearing loss Medicare Source Type: research
Preoperative and postoperative mental health status (MHS) of total joint arthroplasty patients can affect immediate and long-term outcomes following surgery. Alterations in MHS can be acute or chronic. The most common etiologies include acute changes due to (1) delirium or stroke, (2) movement disorders (Alzheimer dementia, Parkinson disease, multiple sclerosis, epilepsy), and (3) mood/behavior disorders (major depressive disorder, anxiety, bipolar disorder, schizophrenia). Across etiologies, alterations in MHS are associated with worse clinical/patient-reported outcomes and greater total cost of care. Prevention via pharm...
Source: Techniques in Orthopaedics - Category: Orthopaedics Tags: Symposium Source Type: research
Conclusion: Interventions directed at the promotion of the QoL of patients with mild AD should focus on the promotion of mindfulness skills in AD patients, in addition to the reduction of psychological morbidity and the promotion of functionality, awareness of the disease, family relationships and social support. PMID: 31411042 [PubMed - as supplied by publisher]
Source: Aging and Mental Health - Category: Geriatrics Authors: Tags: Aging Ment Health Source Type: research
Neuropsychiatric symptoms (NPS) are now recognized as a major component of neurocognitive disorders, such as Alzheimer's disease (AD) and frontotemporal dementia (FTD). NPS in dementia, also referred to as behavioral and psychological symptoms of dementia (BPSD), can take various forms, including: psychotic symptoms, mood disturbances (e.g., depressive symptoms and anxiety), and socially inappropriate behaviours.1,2 NPS are highly prevalent in the course of these disorders, with a large cross-sectional study reporting up to 80% of individuals exhibiting a clinically significant neuropsychiatric manifestation after onset of...
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Regular Research Article Source Type: research
“In my case, symptoms began to appear when I was only 57. In fact, the doctors believe early-onset Alzheimer’s has a strong genetic predictor, and that it may have been progressing for some years before I was diagnosed.” – Pat Summitt  Anyone who’s gone through the experience of a loved one developing Alzheimer’s disease and progressively deteriorating to a shell of their former selves knows how devastating this brain disease is for both patient and those who love and care for him or her.  Memory Performance Changes May Show Up in 20s with Family History of Alzheimer’s St...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Aging Alzheimer's Memory and Perception Alzheimer's disease Dementia Source Type: blogs
DISCUSSION: Dementia subtype is an important predictor of health care costs. Earlier identification and targeted treatment might mitigate the costs associated with co-occurring conditions in LBD. PMID: 31175026 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
Publication date: Available online 5 June 2019Source: Pharmacology Biochemistry and BehaviorAuthor(s): Mitsuhiro Makino, Kaori Takahashi-Ito, Hiroyasu Murasawa, Akiko Pawlak, Yoshinori Kashimoto, Yutaka KitanoAbstractSeveral studies have reported on the beneficial effects of memantine on behavioral and psychological symptoms of dementia (BPSD) in patients with Alzheimer's disease. However, the effects of memantine on BPSD-like behaviors in animals have not been well addressed. Here, the effects of memantine on memory disturbance and BPSD-like behaviors were evaluated in thiamine-deficient (TD) mice. Memantine (3 and 10 m...
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
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