Microhexagon gradient array directs spatial diversification of spinal motor neurons

Conclusions: The differentiated cells showed progressive RNA and protein signatures, consistent with that of representative brachial, thoracic and lumbar regions of the human spinal cord. The microHIVE platform can thus be utilized to develop advanced biomimetic systems for the study of diseases in vitro.

Source: Theranostics - June 13, 2019 Category: Molecular Biology Authors: Geok Soon Lim, Jin Hui Hor, Nicholas R.Y. Ho, Chi Yan Wong, Shi Yan Ng, Boon Seng Soh, Huilin Shao Tags: Research Paper Source Type: research