Comprehensive characterization of the mutational landscape in multiple myeloma cell lines reveals potential drivers and pathways associated with tumor progression and drug resistance

Conclusion: Taken together, this first comprehensive exome-wide analysis of the mutational landscape in HMCLs provides unique resources for further studies and identifies novel genes potentially associated with MM pathophysiology, some of which may be targets for future therapeutic intervention.

Source: Theranostics - June 13, 2019 Category: Molecular Biology Authors: Veronika Vikova, Michel Jourdan, Nicolas Robert, Guilhem Requirand, St é phanie Boireau, Ang é lique Bruyer, Laure Vincent, Guillaume Cartron, Bernard Klein, Olivier Elemento, Alboukadel Kassambara, J é r ô me Moreaux Tags: Research Paper Source Type: research