Abnormal mTORC1 signaling leads to retinal pigment epithelium degeneration
Conclusion: This study revealed that abnormal activation of mTORC1 signaling leads to RPE degeneration, which could provide a promising target for the treatment of RPE dysfunction-related diseases.
Source: Theranostics - Category: Molecular Biology Authors: Jiancheng Huang, Shun Gu, Meng Chen, Shu-jie Zhang, Zhichun Jiang, Xue Chen, Chao Jiang, Guohua Liu, Roxana A Radu, Xiantao Sun, Douglas Vollrath, Jianhai Du, Biao Yan, Chen Zhao Tags: Research Paper Source Type: research