HMGB1-Induced p62 Overexpression Promotes Snail-Mediated Epithelial-Mesenchymal Transition in Glioblastoma Cells via the Degradation of GSK-3 β

Conclusions: This study suggests that p62 is an effector for HMGB1-induced EMT, and may represent a novel therapeutic target in GBM.

Source: Theranostics - June 13, 2019 Category: Molecular Biology Authors: Hong Li, Junjie Li, Guozhong Zhang, Qian Da, Lei Chen, Shishi Yu, Qiang Zhou, Zhijian Weng, Zong Xin, Linyong Shi, Liyi Ma, Annie Huang, Songtao Qi, Yuntao Lu Tags: Research Paper Source Type: research