Repeated ultrasound treatment of tau transgenic mice clears neuronal tau by autophagy and improves behavioral functions

Conclusions: Our findings indicate that a neuronal protein aggregate clearance mechanism induced by ultrasound-mediated blood-brain barrier opening operates for tau, further supporting the potential of low-intensity ultrasound to treat neurodegenerative disorders.

Source: Theranostics - June 13, 2019 Category: Molecular Biology Authors: Rucha Pandit, Gerhard Leinenga, J ü rgen G ö tz Tags: Research Paper Source Type: research