Impaired Regeneration Potential in Urinary Stem Cells Diagnosed from the Patients with Diabetic Nephropathy

Conclusions: Regenerative performance of most d-USC was significantly lower than normal controls. Understanding the specific changes in d-USC regeneration capability will help elucidate the pathobiology of diabetic nephropathy and lead to prevent USC from diabetic insults, recover the stemness function and also identify novel biomarkers to predict progression of this chronic kidney disease.

Source: Theranostics - June 13, 2019 Category: Molecular Biology Authors: Geng Xiong, Weiqing Tang, Deying Zhang, David He, Guanghui Wei, Antony Atala, Xing-Jie Liang, Anthony J. Bleyer, Michael E. Bleyer, Jie Yu, Joseph A. Aloi, Jian-Xing Ma, Cristina M. Furdui, Yuanyuan Zhang Tags: Research Paper Source Type: research