Apparent performance of metagenomic next-generation sequencing in the diagnosis of cryptococcal meningitis: a descriptive study.

CONCLUSION: mNGS is helpful for identifying Cryptococcus species. The application of mNGS, together with India ink staining, culture methods, and CrAg, may significantly improve the diagnostic precision in CM, thereby informing choice of appropriate antifungal treatment courses. PMID: 31184572 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research

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AbstractPurpose of ReviewTo perform an extensive review of recent literature and provide an update on the current epidemiology, clinical features, and management of cryptococcal disease with a focus on the differences between patients depending on their immune status.Recent FindingsEmerging literature has highlighted the inflammatory pathophysiology and varied manifestations of cryptococcal infections in patients who are apparently healthy but paradoxically have a more critical clinical course compared with their immunosuppressed counterparts.SummaryNon-HIV cryptococcal meningitis has greater mortality compared with that s...
Source: Current Fungal Infection Reports - Category: Infectious Diseases Source Type: research
Publication date: Available online 19 July 2019Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Henry Liu, Morgan Brown, Lu Sun, Shukan P. Patel, Jinlei Li, Elyse M. Cornett, Richard D. Urman, Charles J. Fox, Alan David KayeAbstractRegional anesthesia is responsible for approximately one-fifth of professional liability claims. The present investigation evaluated common and rare complications related to regional and neuraxial anesthesia, including postdural puncture headache, backache, transient neurological symptoms, inadvertent intrathecal injection, epidural hematoma and abscess, meningitis, arachno...
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
Authors: Ratre S, Choudhary S, Yadav Y, Parihar V, Bajaj J, Pateria A Abstract Tubercular meningitis (TBM) can have various complications. Sometimes syringomyelia can also occur as a late complication of tubercular meningitis. Although syrinx formation in early stage of TBM is very rare. There are only four published case reports of syringomyelia in acute stage of TBM. Here we report a patient with tubercular meningitis who developed syringomyelia in early course of illness. PMID: 31317721 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Source: International Journal of Tuberculosis and Lung Disease - Category: Respiratory Medicine Authors: Tags: CORRESPONDENCE Source Type: research
Source: International Journal of Tuberculosis and Lung Disease - Category: Respiratory Medicine Authors: Tags: CORRESPONDENCE Source Type: research
CONCLUSIONS Pneumococcal meningitis is probably underdiagnosed and underreported in S ão Paulo. Differentiated rates of pneumococcal meningitis diagnosis and reporting in each microregion, according to the São Paulo Index of Social Responsibility, might explain our results.
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
Group B Streptococcus (GBS) is an important opportunistic bacteria that causes a wide range of infections including neonatal sepsis, meningitis, pneumonia, soft tissue and urinary tract infections (UTI). The aim ...
Source: BMC Research Notes - Category: Research Authors: Tags: Research note Source Type: research
Publication date: Available online 17 July 2019Source: Journal of Global Antimicrobial ResistanceAuthor(s): Paola Vacca, Caterina Vocale, Cecilia Fazio, Luigina Ambrosio, Kety Luzi, Arianna Neri, Annapina Palmieri, Paola Stefanelli
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Laryngo-Rhino-Otol DOI: 10.1055/a-0927-6995Wir berichten über einen 22-jährigen Mann kaukasischer Herkunft, der an unserer Akutambulanz mit Einweisung vom Hausarzt aufgrund eines hochfieberhaften Infekts und Verdacht auf Meningitis vorstellig wurde. Der Patient präsentierte sich verwirrt und lichtempfindlich. Es bestanden immer wieder somnolente Phasen, Fieber konnte bei Novalgin-Einnahme zum Aufnahmezeitpunkt keines gemessen werden. Der Patient war zudem tachypnoisch, es bestand bei der klinisch-neurologischen Untersuchung ein deutlicher Meningismus. Zusätzlich war eine prominente Schwellung des rechte...
Source: Laryngo- Rhino- Otologie - Category: ENT & OMF Authors: Tags: Der interessante Fall Source Type: research
Conclusion: Colo-epidural fistula can occur as a consequence of colorectal anastomotic leakage. Prior to frank neurology symptoms and sepsis, patients may present with only a low-grade fever. Without prompt and aggressive management of colo-epidural infection, this severe complication can lead to paraplegia and death. PMID: 31311450 [PubMed - as supplied by publisher]
Source: Acta Chirurgica Belgica - Category: Surgery Tags: Acta Chir Belg Source Type: research
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