Comparison of Intralesional Triamcinolone Acetonide, Botulinum toxin type A, and Their Combination for the Treatment of Keloid lesions.

Conclusion: Combined injection of intralesional steroids with BTX-A appears to be superior to either therapy alone and offer the best benefit of safer and more efficacious response with lesser side effects. PMID: 31184533 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research

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AbstractMost of the widely used scales to evaluate scars are subjective relying on clinical observations. There is a growing need to find out a noninvasive objective tool for this purpose. The study is aimed at evaluating the value of the high-resolution ultrasound in the assessment of the scars when compared with a clinical evaluation scoring system, the Vancouver Scar Scale (VSS). The study included 22 patients with hypertrophic scars or keloids. At baseline, scars were assessed using the Vancouver Scar Scale and high-resolution ultrasound (13-MHz probe). Patients received three Nd:YAG laser sessions (100  J/cm2 flu...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
​Some procedures are worth doing over and over because they are easy and fun. The bonus is they can improve outcomes for patients and prevent bouncebacks, costly follow-up exams, and prolonged pain and complications. This month we discuss the use of the ultrasound (US) water bath and bedside imaging for foreign bodies (FB). If you would like to see more about using ultrasound for FBs, see our previous blog post about wine glass in the foot. (http://bit.ly/2HSQLvZ.)​Bedside US is an exquisite technique that can be used to examine and explore numerous parts of the body without using radiation. This procedure uses a simpl...
Source: The Procedural Pause - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
CONCLUSION Objective measurements of relevant keloid characteristics as height, volume, and penetration depth help in quantifying the therapeutic effect. The observed results confirm that intralesional injections of crystalline triamcinolone acetonide combined with cryotherapy represent a powerful approach to reduce scar height and volume significantly.
Source: Dermatologic Surgery - Category: Dermatology Tags: Original Article Source Type: research
Centella asiatica (Centellicum®) facilitates the regular healing of surgical scars in subjects at high risk of keloids. Minerva Chir. 2018 Apr;73(2):151-156 Authors: Cotellese R, Hu S, Belcaro G, Ledda A, Feragalli B, Dugall M, Hosoi M, Ippolito E Abstract BACKGROUND: Formation of scars after surgical incisions requires the proper appositions of elements contributing to the scarring process. The structural rebuilding of damaged tissues is essential in producing a linear scar. The excess of blood, foreign particles, exuberant sutures, necrotic tissue, possible infective agents, as well as the ongoin...
Source: Minerva Chirurgica - Category: Surgery Tags: Minerva Chir Source Type: research
[Image from unsplash.com]From Hologic’s new product launch to CapsoVision gettting CE Mark approval, here are seven medtech stories we missed this week but thought were still worth mentioning. 1. Hologic launches new MyoSure device Hologic announced in a Nov. 1 press release that it has launched its MyoSure Manual Device in the U.S. The device is designed to help doctors resect and remove intrauterine tissue easily in an office setting if used with the MyoSure hysteroscope. 2. IntraFuse wins FDA clearance for FlexThread fibula pin IntraFuse has received FDA 510(k) clearance for its FlexThread Fibula Pin System, ...
Source: Mass Device - Category: Medical Devices Authors: Tags: 510(k) Endoscopic / Arthroscopic Oncology Orthopedics Pain Management Regulatory/Compliance Surgical Ultrasound Women's Health brhmedical CapsoVision Helomics Hologic Inc. IntraFuse MedTech Sensus Healthcare LLC Skyline Med Source Type: news
CONCLUSION: Color Doppler ultrasound can support the assessment of activity in keloids. Clinical evaluation alone can underestimate the activity in keloids. Relevant anatomical and subclinical features can be detected by CDU.
Source: Dermatologic Surgery - Category: Dermatology Tags: Original Article Source Type: research
We evaluated nodular fasciitis (NF) in 19 patients, focusing on the correlation between its sonographic and histopathologic features. Sonograms were retrospectively reviewed, and the location, shape, margin, echogenicity, echogenic rim, peripheral hyper-echoic nodules, posterior enhancement and vascularity of the lesions were  recorded. In the histopathologic analysis, three patterns—infiltrating, pushing border and well circumscribed—were identified, and culture-like tissue centers were classified according to the distribution of focal keloid-like collagen bundles: uneven or even.
Source: Ultrasound in Medicine and Biology - Category: Radiology Authors: Tags: Clinical Note Source Type: research
OBJECTIVE: To evaluate the individual effectiveness of needling therapy using the Dermapen (Dermapen, Salt Lake City, Utah) and topical therapy with silicone gel (Kelo-cote, Sinclair Pharma, London, England), and their combined effectiveness for the treatment of linear surgical scars, hypertrophic scars, and keloids. MATERIALS AND METHODS: Twenty patients were randomly selected and equally divided into 2 groups (A and B), with each group of 10 including 6 patients with keloids and 4 with hypertrophic scars. Treatment assignments were random. In group A, the entire scar was treated by skin needling, with silicone gel appli...
Source: Advances in Skin and Wound Care - Category: Dermatology Tags: Features: Original Investigations Source Type: research
Abstract BackgroundThe current treatment of keloids includes surgery, intralesional steroids, and radiotherapy, among others. Radiotherapy is not recommended in children due to its effects on growing tissues. Our aim was to study intralesional triamcinilone therapy of keloids in children and analyze the impact of body location, age of the lesion, and etiology of the keloid on clinical response. MethodsWe conducted a prospective clinical trial with patients 1 to 14 years of age evaluated for keloid treatment. A soft tissue ultrasound was performed to measure the keloid volume, prior to intralesional infiltration with triamc...
Source: Pediatric Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
Conclusions: Shear wave elastography provides quantitative estimates of tissue stiffness that correlate with the clinical symptoms and histopathological findings of the keloid lesions and can be used to assess the activity of keloids.
Source: Plastic and Reconstructive Surgery Global Open - Category: Cosmetic Surgery Tags: Ideas and Innovations Source Type: research
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