Genetic testing to resolve the source of haemolytic antibody in solid organ transplantation.

DISCUSSION: Passenger lymphocyte syndrome after mismatched organ transplantation is not rare, but the syndrome associated with non-ABO antibodies occurs in a much smaller subset of these cases. The mixtures of organ donor, recipient, and other transfused red blood cells profoundly limit the usefulness of serological testing. Genetic assignment of minor blood types to donor and recipient can guide therapy and inform prognosis. PMID: 31184578 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31184578?dopt=Abstract

Source: Blood Transfusion - June 4, 2019 Category: Hematology Authors: Tsang HC, Samraj AN, Morse RJ, Krumm N, Hess JR, Pagano MB Tags: Blood Transfus Source Type: research