Additional Chemotherapy with 5-FU plus Leucovorin between Preoperative Chemoradiotherapy and Surgery Improved Treatment Outcomes in Patients with Advanced Rectal Cancer

Conclusions: This preliminary study showed that additional preoperative chemotherapy with LV5FU2 was well tolerable and had an improvement in the downstaging rate and survival. Randomized controlled trial of this strategy is encouraged for definitive conclusions.

Source: Journal of Cancer - June 13, 2019 Category: Cancer & Oncology Authors: Song Ee Park, Jin Hwa Choi, Chang Hwan Choi, Suk Won Park, Beon Gyu Kim, Seong Jae Cha, In Gyu Hwang Tags: Research Paper Source Type: research