Association of SMUG1 SNPs in Intron Region and Linkage Disequilibrium with Occurrence of Cervical Carcinoma and HPV Infection in Chinese Population

Conclusions: These findings suggested that there was association between the two genetic polymorphisms of SMUG1 rs3087404(A/G) and rs2029167(A/G) with the susceptibility of CIN III and CSCCs, and there was a linkage disequilibrium between the rs3087404 with the rs2029167 in CIN III and CSCCs. This particular linkage disequilibrium can be used as predictive biomarkers of CIN III and CSCC.

Source: Journal of Cancer - June 13, 2019 Category: Cancer & Oncology Authors: Feng Ye, Hanzhi Wang, Jia Liu, Qi Cheng, Xiaojing Chen, Huaizeng Chen Tags: Research Paper Source Type: research