Mutation Profiling of Malignant Lymphoma by Next-Generation Sequencing of Circulating Cell-Free DNA

Conclusion: Our findings demonstrate that NGS-based cfDNA mutation profiling reveals genetic heterogeneity across lymphoma subtypes, with potential implications for the discovery of therapeutic targets, the exploration of genome evolution and the development of risk-adapted treatment.

Source: Journal of Cancer - June 13, 2019 Category: Cancer & Oncology Authors: Peng Sun, Cui Chen, Yi Xia, Yu Wang, Pan-Pan Liu, Xi-Wen Bi, Yang W. Shao, Qiu-Xiang Ou, Xue Wu, Hang Yang, Man Nie, Xue-Wen Zhang, Zhi-Ming Li, Wen-Qi Jiang Tags: Research Paper Source Type: research