Aberrant Activation Of Hedgehog Signalling Promotes Cell Migration And Invasion Via Matrix Metalloproteinase-7 In Ovarian Cancer Cells

Conclusion: Aberrant activation of the Hh-Gli-MMP-7 signalling axis is essential for acceleration of the progression and metastasis of human ovarian cancer, implicating its use as a novel therapeutic target of ovarian cancer. In addition, MMP-7 can potentially serve as a prognostic marker of ovarian cancer.

Source: Journal of Cancer - June 13, 2019 Category: Cancer & Oncology Authors: Hong Zhang, Yiting Wang, Tingtao Chen, Yan Zhang, Rong Xu, Wanwan Wang, Minzhang Cheng, Qi Chen Tags: Research Paper Source Type: research