PD-L1 expression patterns in tumour cells and their association with CD8+ tumour infiltrating lymphocytes in clear cell renal cell carcinoma

Conclusion: The intrinsic and extrinsic expression patterns are both detected in ccRCC. High positive rate of TC-PD-L1 correlated closely to the strong infiltration of CD8+ TILs. TC-PD-L1-positive ccRCC patients with abundant CD8+ TILs infiltration confer the high risk of death and disease relapse.

Source: Journal of Cancer - June 13, 2019 Category: Cancer & Oncology Authors: Qian Zhu, Mu-Yan Cai, De-Sheng Weng, Jing-Jing Zhao, Qiu-Zhong Pan, Qi-Jing Wang, Yan Tang, Jia He, Min Li, Jian-Chuan Xia Tags: Research Paper Source Type: research