The Efficacy of Upfront Intracranial Radiation with TKI Compared to TKI Alone in the NSCLC Patients Harboring EGFR Mutation and Brain Metastases

Conclusion: Compared to upfront intracranial RT, the salvage RT to oligo-progressive disease allowed patients getting TKI to have similar time on initial TKI and OS despite worse iPFS. The best timing of intracranial RT remains to be further verified.

Source: Journal of Cancer - June 13, 2019 Category: Cancer & Oncology Authors: Chunyu Wang, Xiaotong Lu, Zongmei Zhou, Jingbo Wang, Zhouguang Hui, Jun Liang, QinFu Feng, Dongfu Chen, Zefen Xiao, Jima Lv, Xiaozhen Wang, Xin Wang, Tao Zhang, Lei Deng, Wenqing Wang, Jianping Xiao, Junling Li, Nan Bi, Luhua Wang Tags: Research Paper Source Type: research