Human Leukocyte Antigen (HLA) Class II -DRB1 and -DQB1 Alleles and the Association with Cervical Cancer in HIV/HPV Co-Infected Women in South Africa

Conclusion: We describe associations between HLA class II genotypes with cervical cancer, or likely protection from cervical cancer disease in HIV/HPV co-infected South African women. Identifying mechanisms that give rise to this likely protective HLA association will provide insight into development of immune-based prevention measures.

Source: Journal of Cancer - June 13, 2019 Category: Cancer & Oncology Authors: Ramadhani Chambuso, Raj Ramesar, Evelyn Kaambo, Lynette Denny, Jo-Ann Passmore, Anna-Lise Williamson, Clive M Gray Tags: Research Paper Source Type: research