Five Day Accelerated Partial Breast Irradiation (APBI) Using Stereotactic Body Radiation Therapy (SBRT) in Stage 0-II Breast Cancer: A Preliminary Report of 53 Cases

Randomized trials in selected early stage breast cancer patients with up to 10 year follow-up have proven that Accelerated Partial Breast Irradiation (APBI) given via High Dose Rate (HDR) implant bid in 5 days is equivalent to whole breast External Radiation Therapy (XRT) given qd in 5-6 weeks in regard to breast tumor local recurrence (LR) [1-2]. However, complications with APBI implant in a Medicare database review have been significant, with 3.95% of women requiring Mastectomy, 16.2% developing infections, and another 16.3% experiencing non-infection complications including rib fractures, fat necrosis, and breast pain [3].
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research

Related Links:

ConclusionsWomen with non-dominant BC use their involved limb similar to healthy controls but less than their dominant limb.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
ConclusionPEGylated G-CSF was as effective and safe as G-CSF to reduce CIN in breast cancer but did not show an obvious superiority. However, in clinical practice, PEGylated G-CSF has an obvious advantage in terms of convenience, which could improve patient ’s quality of life.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
ConclusionThe postoperative protocol with free shoulder ROM on the 15th day after surgery is safe and beneficial in terms of kinetic-functional recovery and pain control for patients after mastectomy and immediate implant-based reconstruction.Clinical Trials RegisterNCT02480842
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
AbstractOpioid overdose accounted for more than 47,000 deaths in the United States in 2018. The risk of new persistent opioid use following breast cancer surgery is significant, with up to 10% of patients continuing to fill opioid prescriptions one year after surgery. Over prescription of opioids is far too common. A recent study suggested that up to 80% of patients receiving a prescription for opioids post-operatively do not need them (either do not fill the prescription or do not use the medication). In order to address this important issue, The American Society of Breast Surgeons empaneled an inter-disciplinary committe...
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
Authors: Xu J, Li D, Du K, Wang J Abstract Background: Cinobufacin is a Chinese patent medicine widely used for breast cancer in China. However, no systematic review and meta-analysis have been published to validate its effects in breast cancer treatment. We, therefore, summarize the efficacy and safety of Cinobufacin combined with chemotherapy in order to provide rigid evidence for its clinical application. Methods: By searching multiple databases incepted to December 2019, the RCTs of breast cancer patients treated with Cinobufacin were screened according to the inclusion criteria, and the meta-analysis and s...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
A 55-year-old woman with back pain underwent 18F-NaF PET/CT study to evaluate bone metastases from newly diagnosed breast cancer. Multiple foci of increased tracer uptake indicating osteoblastic metastases were noted in cervical and thoracic vertebrae. Unexpectedly, breast cancer also revealed increased NaF activity.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
This study aimed to prospectively explore severity and prevalence of chemotherapy-induced peripheral neuropathy (CIPN) and examine the correlation between clinician-assessed (objective) and patient-reported (subjective) CIPN in breast cancer survivors receiving taxane.MethodsThis was a prospective, longitudinal study. Purposive sampling was adapted to enroll women newly diagnosed with breast cancer and about to receive taxane. The CIPN was assessed after breast cancer diagnosed and before chemotherapy (T1), before cycle 1 to 4 taxane infusion (T2 to T5), and after chemotherapy completion (T6 to T8). Total Neuropathy Score ...
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
Analyze the effects of a 12-week dance intervention on the sleep quality and the level of pain among women with breast cancer.
Source: Journal of Bodywork and Movement Therapies - Category: Physiotherapy Authors: Tags: Prevention and Rehabilitation Source Type: research
This study aimed to explore the use of thermal imaging in treatment for BCRL. The swollen arms of two participants with BCRL were photographed using a thermal imaging camera during a single RLD treatment. Limb Volume Circumferential Measurement (LVCM) of both arms was taken before, after and the next day. The images were examined for visual changes, and temperature data were extracted. Images showed differences in temperature within the affected hand and arm over 45 minutes. LVCM data indicated a loss of limb volume in the affected arm in both cases, which continued to decrease over 24 hours. Thus, thermal imaging may be u...
Source: British Journal of Community Nursing - Category: Nursing Authors: Tags: Br J Community Nurs Source Type: research
Background: Implant-based breast reconstruction (IBBR) after mastectomy either with TE or DTI in pre-pectoral position has been widely accepted. The pre-pec breast reconstruction, in fact, spares muscles, preserving the natural anatomy and reduces post-operative pain. Moreover, the pre-pec approach is associated to a decreased risk of capsular contracture and animation deformities. An increasing number of women, who undergo IBBR, will require post mastectomy radiotherapy (PMRT), since the meta-analysis of Early Breast Cancer Trialists ’ Collaborative Group (EBCTCG) confirmed a significant reduction of both local recu...
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: CLINICAL SCIENCE SYMPOSIUM: Implants Source Type: research
More News: Brachytherapy | Breast Cancer | Cancer | Cancer & Oncology | Databases & Libraries | Mastectomy | Medicare | Pain | Radiation Therapy | Women