Evaluation of Serum Prostate-Specific Membrane Antigen Levels in Patients Receiving Brachytherapy for Localized Prostate Cancer

Prostate-specific membrane antigen-positron emission tomography (PSMA-PET) imaging has already been integrated into the routine diagnostic workup of prostate cancer in Western countries. Increased PSMA expression in prostate tissues is associated with tumor aggressiveness. However, the serum level of PSMA are usually 50- to 100-fold lower than those of PSA. Therefore, the changes in the serum level of PSMA after brachytherapy and hormonal therapy in patients are unknown. Here, we investigated the serum PSMA level in prostate cancer patients treated by brachytherapy and/or hormonal therapy.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research