Long non-coding RNA GHET1 contributes to chemotherapeutic resistance to Gemcitabine in bladder cancer

ConclusionsHigh expression of GHET1 was related with the low sensitivity to Gemcitabine of BC; GHET1 contributed to chemotherapeutic resistance to Gemcitabine in BC through up-regulating ABCC1 expression. Our findings are helpful to expound the molecular mechanism of chemotherapeutic resistance in BC.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research