Association between Tumor Acidity and Hypervascularity in Human Gliomas Using pH-Weighted Amine Chemical Exchange Saturation Transfer Echo-Planar Imaging and Dynamic Susceptibility Contrast Perfusion MRI at 3T [FUNCTIONAL]

CONCLUSIONS:
A positive linear correlation between CBV and acidity in areas of T2-hyperintense, nonenhancing tumor, but not enhancing tumor, was observed across patients. Local heterogeneity was observed within individual tumors.

Source: American Journal of Neuroradiology - June 11, 2019 Category: Radiology Authors: Wang, Y.- L., Yao, J., Chakhoyan, A., Raymond, C., Salamon, N., Liau, L. M., Nghiemphu, P. L., Lai, A., Pope, W. B., Nguyen, N., Ji, M., Cloughesy, T. F., Ellingson, B. M. Tags: FUNCTIONAL Source Type: research