Creutzfeldt –Jakob disease‐like diffusion‐weighted imaging hyperintensity paralleled with neuropsychiatric symptoms in a patient with limbic encephalitis associated with anti‐voltage‐gated potassium channel complex antibodies

In this report, we describe a case of a 58 ‐year‐old man with limbic encephalitis associated with anti‐voltage‐gated potassium channel complex antibodies (anti‐VGKCC‐ab). He exhibited clinical and diffusion‐weighted imaging (DWI) findings suspicious for Creutzfeldt‐Jakob disease (CJD). Unlike similar reported cases, DWI findi ngs paralleled with neuropsychiatric clinical symptoms. Our case emphasizes the importance of anti‐VGKCC‐ab‐associated encephalitis as a differential diagnosis of CJD.

Source: Clinical and Experimental Neuroimmunology - June 11, 2019 Category: Neurology Authors: Toshiki Okadome, Taira Uehara, Koji Shinoda, Ken ‐Ichiro Yamashita, Hiroyuki Murai, Noriko Isobe, Ryo Yamasaki, Jun‐Ichi Kira Tags: Images in Neuroimmunology Source Type: research