Use of MitraClip in the Percutaneous Treatment of Severe Mitral Regurgitation in Heart Transplant Recipients

Publication date: Available online 11 June 2019Source: Revista Española de Cardiología (English Edition)Author(s): Miguel Salas, Gerard Roura, Dabit Arzamendi, Javier Berdejo, Nicolás Manito, Joan Antoni Gómez-Hospital
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research

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ConclusionWe observed a high frequency of RV dysfunction in a sample of potential heart donors. However, the temporal evolution of RV dysfunction, the hemodynamic predictors of RV dysfunction, as well the link between donor RV dysfunction and recipient outcomes need to be assessed with further prospective studies.
Source: Journal of Critical Care - Category: Gastroenterology Source Type: research
The year before four transplant cardiologists resigned from OHSU Hospital, the program experienced twice the number of patient deaths than expected, according to a report in The Oregonian. People who received a heart transplant at the hospital in the last two years are at 67 percent higher risk to die in the first year after the procedure than patients at comparable programs, according to The Oregonian, citing a July 2019 report from the Scientific Registry of Transplant Recipients. OHSU put the…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
In conclusion, we show here that sEVs are responsible for mediating paracrine senescence and speculate that they could be involved in inducing bystander senescence during therapy-induced senescence or aging. In fact, when compared to soluble factors, sEVs have different biophysical and biochemical properties as they have a longer lifespan than do soluble factors and they are more resistant to protease degradation. The idea that blocking sEV secretion could be a potential therapeutic approach to alleviate senescence "spreading" during chemotherapy-induced senescence or in aging tissues presents itself as a very at...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
AbstractStem cell transplantation in regenerative medicine has been widely used in various disorders including cardiovascular diseases (CVD) and emerging next-generation therapy. However, transplanted stem cell encountered ischemia/reperfusion (IR) injury which is a major challenge for stem cell survival. During the acute phase after myocardial infarction (MI) cytokine –rich hostile microenvironment, extensive immune cell infiltration and lack of oxygen have been a bottleneck in cell-based therapy. During prolonged ischemia, intracellular pH and ATP level decrease results in anaerobic metabolism and lactate accumulat...
Source: Heart Failure Reviews - Category: Cardiology Source Type: research
Publication date: May–June 2019Source: Journal of Clinical and Experimental Hepatology, Volume 9, Issue 3Author(s): V. Sagar Puppala, Sasidhar Reddy L, Manish C. Varma, Manjunath B, Anand Khakkar, Mahesh Gopashetty, Anand Ramamurthy, Girish Warrier, Kavitha Chintala, Meena Trehan
Source: Journal of Clinical and Experimental Hepatology - Category: Gastroenterology Source Type: research
Authors: Komatsu M, Yamamoto H, Shomura T, Sonehara K, Ichiyama T, Urushihata K, Ushiki A, Yasuo M, Wakamatsu T, Sugimoto S, Oto T, Date H, Koizumi T, Hanaoka M, Kubo K Abstract Patients with end-stage lung disease can undergo living-donor lobar lung transplantation (LDLLT), with survival rates improving every year. We herein report the 20-year follow-up findings of the first patient who underwent LDLLT in Japan. A 24-year-old woman with primary ciliary dyskinesia became ventilator-dependent after severe respiratory failure and right-sided heart failure following repeated respiratory infections. In 1998, she underw...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
CONCLUSION: In our first Asian-Pacific real-world data, automated dynamic CRT optimization showed comparable efficacy to conventional methods regarding clinical outcomes and electromechanical remodeling. PMID: 31293111 [PubMed - in process]
Source: J Korean Med Sci - Category: General Medicine Authors: Tags: J Korean Med Sci Source Type: research
Abstract INTRODUCTION AND OBJECTIVE: Pulmonary hypertension (PH) complicating idiopathic pulmonary fibrosis (IPF) is challenging to diagnose given inaccuracy of transthoracic echocardiogram (TTE) measurements. However, it has significant prognostic implications and is therefore important to accurately identify. METHODS: We conducted a cross-sectional study of patients with IPF who underwent RHC as part of their evaluation. A variety of commonly available noninvasive variables were evaluated for their ability to predict pulmonary arterial pressure in a linear regression model, including the traditionally used ...
Source: Respiratory Care - Category: Respiratory Medicine Authors: Tags: Clin Respir J Source Type: research
AbstractIntroduction and ObjectivePulmonary hypertension (PH) complicating idiopathic pulmonary fibrosis (IPF) is challenging to diagnose given inaccuracy of transthoracic echocardiogram (TTE) measurements. However, it has significant prognostic implications and is therefore important to accurately identify.MethodsWe conducted a cross ‐sectional study of patients with IPF who underwent RHC as part of their evaluation. A variety of commonly available noninvasive variables were evaluated for their ability to predict pulmonary arterial pressure in a linear regression model, including the traditionally used right ventricular...
Source: The Clinical Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research
DISCUSSION: The clinical, genetic, and muscle biopsy findings suggest that both mutations are pathogenic. The EXT2 mutation was most likely responsible for the multiple exostoses phenotype in mother and son, whereas the myopathy was probably caused by a combined effect of the LMNA and EXT2 mutations.
. PMID: 31296281 [PubMed - as supplied by publisher]
Source: Clinical Neuropathology - Category: Pathology Authors: Tags: Clin Neuropathol Source Type: research
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