Pregnancy outcomes of adolescent primigravida and risk of pregnancy-induced hypertension: a hospital-based study in Southern Thailand.

The objectives were to examine pregnancy outcomes in adolescent primigravida and to determine the effects of adolescent pregnancy on pregnancy-induced hypertension (PIH). A retrospective analysis of pregnancy outcomes was carried out in 2440 adolescent primigravida, compared with 14,259 primigravida aged 20-29 years. The adolescents had significantly higher rates of maternal death, maternal heart disease, PIH, puerperal infection, chorioamnionitis, urinary tract infection, foetal anomaly, preterm delivery, low birth weight, low Apgar scores and stillbirth. Multivariate logistic regression analysis showed that both older (16-19 years old) and younger (≤15 years old) adolescents were significantly at an increased risk of PIH (adjusted OR of 1.29; 95% CI, 1.03-1.62 and 1.90; 95% CI, 1.02-3.54, respectively). Adolescent primigravida had significantly lower rates of caesarean delivery, diabetes mellitus, chronic hypertension, placenta praevia and cephalopelvic disproportion (CPD). Inadequate antenatal care in adolescents increased rates of PIH and adverse foetal outcomes. Impact statement What is already known on this subject? Adolescent pregnancy is associated with adverse pregnancy outcomes in both mothers and foetuses. Conflicting evidence on some adverse maternal outcomes still exists. What the results of this study add? Our data suggest a significant increase risk of pregnancy-induced hypertension (PIH) in both younger and older adolescent primigravida. Inad...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research

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DiscussionWe estimated higher risks of ALL in the offspring of women with pregestational diabetes. These results are consistent with previous findings and compatible with a role of prenatal glycaemic environment in childhood cancer aetiology.
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
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Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
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Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
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Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
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Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
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Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
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