Flagellar Hook/Needle Length Control and Secretion Control in Type III Secretion Systems.

Flagellar Hook/Needle Length Control and Secretion Control in Type III Secretion Systems. Curr Top Microbiol Immunol. 2019 Jun 11;: Authors: Aizawa SI Abstract The flagellum is a motile organ, and the needle complex is a type III secretion apparatus for pathogenesis. There are more similarities than differences between the two structures at the molecular level. Here I focus on the hook and the needle and discuss their length control mechanism. The hook is a substructure of the flagellum and the needle is a part of the needle complex. Both structures are tubular structures that have a central channel for protein secretion. Their lengths are controlled by an intriguing mechanism involving a ruler protein and a switchable gate of the protein secretion system. A model for length control is proposed. PMID: 31183607 [PubMed - as supplied by publisher]
Source: Current Topics in Microbiology and Immunology - Category: Microbiology Tags: Curr Top Microbiol Immunol Source Type: research