Conquering the Craving: Treatment to Curb Alcohol Use Disorder

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Source: Journal of Christian Nursing - Category: Nursing Tags: CE Connection Source Type: research

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Conclusion: In this study, frequent regular use of over-the-counter mouthwash was associated with increased risk of hypertension, independent of major risk factors for hypertension and several other potential confounders. PMID: 31709856 [PubMed - as supplied by publisher]
Source: Blood Pressure - Category: Hematology Tags: Blood Press Source Type: research
Publication date: Available online 11 November 2019Source: Spatial and Spatio-temporal EpidemiologyAuthor(s): Yusuf Ransome, S.V. Subramanian, Dustin T. Duncan, Daivid Vlahov, Joshua WarrenAbstractDrug- and alcohol-poisoning deaths remain current public health problems. Studies to date have typically focused on individual-level predictors of drug overdose deaths, and there remains a limited understanding of the spatiotemporal patterns and predictors of the joint outcomes. We use a hierarchical Bayesian spatiotemporal multivariate Poisson regression model on data from (N=167) ZIP-codes between 2009 and 2014 in New York City...
Source: Spatial and Spatio-temporal Epidemiology - Category: Epidemiology Source Type: research
Publication date: Available online 11 November 2019Source: The LancetAuthor(s): Stephen A Harrison, Mustafa R Bashir, Cynthia D Guy, Rong Zhou, Cynthia A Moylan, Juan P Frias, Naim Alkhouri, Meena B Bansal, Seth Baum, Brent A Neuschwander-Tetri, Rebecca Taub, Sam E MoussaSummaryBackgroundNon-alcoholic steatohepatitis (NASH) is characterised by hepatic steatosis, inflammation, hepatocellular injury, and progressive liver fibrosis. Resmetirom (MGL-3196) is a liver-directed, orally active, selective thyroid hormone receptor-β agonist designed to improve NASH by increasing hepatic fat metabolism and reducing lipotoxicity....
Source: The Lancet - Category: General Medicine Source Type: research
ConclusionThe findings indicate diversity in patient views on EHR sensitivity and data sharing preferences and the need for more granular and patient-centered electronic consent mechanisms to accommodate patient needs. More research is needed to validate the generalizability of the proposed methodology.Graphical abstract
Source: Journal of Biomedical Informatics - Category: Information Technology Source Type: research
Conclusions: Alcohol use was prevalent and under-reported among pregnant WLWH in South Africa and Uganda, similar to nonpregnant participants, and associated with depression. General health care and antenatal clinic settings present opportunities to provide integrated alcohol-based counseling and depression treatment.
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - Category: Infectious Diseases Tags: Clinical Science Source Type: research
ConclusionsMothers ’ chronic and excessive postpartum alcohol consumption during early parenthood can be a significant risk factor for difficulties in children’s early executive function development. Early screening for mothers with unhealthy alcohol consumption habits is critical. Special attention and support sh ould be afforded to their children’s development and school adjustment.
Source: Social Psychiatry and Psychiatric Epidemiology - Category: Psychiatry Source Type: research
Publication date: Available online 11 November 2019Source: Journal of Prosthodontic ResearchAuthor(s): Ana C. Cadore-Rodrigues, Luís F. Guilardi, Vinicius F. Wandscher, Gabriel K.R. Pereira, Luiz F. Valandro, Marília P. RippeAbstractPurposeTo compare the effect of different surface treatments (pre-treatments and bonding agents) on the bond strength between glass-fiber post and composite resin, and the topographic alterations of the treated post surface.MethodsThirty-six glass-fiber blocks (12 mm × 10 mm × 8 mm) were specifically manufactured for this study and ra...
Source: Journal of Prosthodontic Research - Category: Dentistry Source Type: research
Funding Opportunity RFA-AA-20-006 from the NIH Guide for Grants and Contracts. The goal of this FOA is to support basic and clinical research on the influence of alcohol on susceptibility and progression of Alzheimers disease and its related dementias. Recent longitudinal studies have provided strong evidence that alcohol use disorder is associated with the high risk of all types of dementias, and frequent heavy drinking increases risk of both Alzheimers disease and vascular dementia. Even moderate alcohol consumption may be a risk factor for adverse brain outcomes and cognitive decline. Although these studies link heavy ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
In this study, it was found that acetaldehyde treatment induced excessive mitochondrial fragmentation, impaired mitochondrial function and caused cytotoxicity in cortical neurons and SH-SY5Y cells. Further analyses showed that acetaldehyde induced the phosphorylation of mitochondrial fission related protein dynamin-related protein 1 (Drp1) at Ser616 and promoted its translocation to mitochondria. The elevation of Drp1 phosphorylation was partly dependent on the reactive oxygen species (ROS)-mediated activation of c-Jun-N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK), as N-acetyl-l-cysteine (NAC) pre...
Source: Redox Biology - Category: Biology Source Type: research
Publication date: Available online 11 November 2019Source: European Polymer JournalAuthor(s): Fuhua Xin, Meng Wei, Shengling Jiang, Yanjing Gao, Jun Nie, Yuejiao Wu, Fang SunAbstractThree kinds of hydrophilic photocleavage o-nitrobenzyl acrylate-modified nanogels with different particle size and narrow particle size distribution (1.8-0.24) were designed and synthesized by reversible addition-fragmentation chain transfer radical (RAFT) polymerization based on methoxy polyethylene glycol methacrylate (MPEGMA) and UV-light responsive crosslinker 5-(acryloyloxy)-2-nitrobenzyl acrylate (ONB) prepared with acryloyl chloride and ...
Source: European Polymer Journal - Category: Chemistry Source Type: research
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