Medical News Today: What to know about secondary progressive multiple sclerosis (SPMS)

This article provides an overview of the condition, including its symptoms, diagnosis, and treatments.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

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Purpose We determined if a high-intensity aerobic exercise program would be safe, improve expected fitness and clinical outcomes, and alter exploratory phosphorous magnetic resonance spectroscopy (31P MRS) outcomes in persons with multiple sclerosis (PwMS). Methods This open-label prospective pilot study compared two cohorts of ambulatory PwMS matched for age, sex and V˙O2max. Cohorts underwent 8 wk of high-intensity aerobic exercise (MS-Ex, n = 10) or guided stretching (MS-Ctr, n = 7). Aerobic exercise consisted of four 30-min sessions per week while maintaining ≥70% maximal HR. Changes in cardiorespiratory fitne...
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: CLINICAL SCIENCES Source Type: research
Conclusions: We revealed that the genotypes of CETPrs708272 G/A, IL6rs1800795 G/G, and each allele C at VEGFArs833068 were associated with ON. CETPrs708272 G/G genotype was associated with decreased by 62% odds of ON with MS development under the recessive (OR = 0.379;95%CI:0.155-0.929; p = .034) model. PMID: 31199170 [PubMed - as supplied by publisher]
Source: Ophthalmic Genetics - Category: Opthalmology Tags: Ophthalmic Genet Source Type: research
Authors: Ayrignac X, Bilodeau PA, Prat A, Girard M, Labauge P, Le Lorier J, Larochelle C, Duquette P Abstract Introduction: The number of immunomodulatory options approved for multiple sclerosis (MS) has increased over the past 24 years, resulting in a better control of the disease. Depending on disease activity, neurologists can now propose treatments with different levels of efficacy, from injectable and oral treatments with modest efficacy, to highly active immunosuppressants and monoclonal antibodies which can be used as induction therapies. Nevertheless, this gain in efficacy has come with an increase in the glob...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research
MRI studies show multiple sclerosis brain changes linked to depression, but randomized controlled trials of antidepressants in this population are lacking.Medscape Medical News
Source: Medscape Psychiatry Headlines - Category: Psychiatry Tags: Neurology & Neurosurgery News Source Type: news
Treatment options for multiple sclerosis (MS) flares include steroids. These can help reduce symptoms such as visual disturbances and weakness. Their effectiveness is relatively high. Learn more about steroids for MS here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news
The recently approved disease-modifying therapy is expected to find a niche for patients with multiple sclerosis who fail other agents.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news
I just cannot understand why it is so difficult to get people to grasp what seems to me a simple idea. Let's try one more time.The purpose of insurance is to spread risk. That's the essence of the concept. Health insurance (or health care insurance as some prefer to say) is different from other kinds of insurance in some ways, so let's just talk about health insurance.Health care costs are unpredictable. It is true that there are risk factors associated with some conditions, most notably smoking tobacco. Nevertheless, no matter how healthful your lifestyle, you still just might need expensive health care. You might be hit ...
Source: Stayin' Alive - Category: American Health Source Type: blogs
Publication date: Available online 13 June 2019Source: BiologicalsAuthor(s): Muhammad K. Nisar
Source: Biologicals - Category: Biology Source Type: research
Researchers at Ben-Gurion University of the Negev (BGU) and Cedars-Sinai Medical Center in Los Angeles said that for the first time they have duplicated a patient's blood-brain barrier (BBB) with stem cells. In turn, the research team said this can be used to develop personalized medicine and new techniques to research brain disorders. The new research, published in the journal Cell Stem Cell, is a collaboration between Dr. Gad Vatine of BGU's Regenerative Medicine and Stem Cell Research Center and Department of Physiology and Cell Biology and Dr. Clive N. Svendsen, of Cedars-Sinai Medical Center in Los Angeles. The BBB bl...
Source: MDDI - Category: Medical Devices Authors: Tags: Imaging Source Type: news
Multiple sclerosis (MS) is a neurological disease of the central nervous system and is associated with many psychosocial symptoms that are difficult to manage including low mood, anxiety, fatigue and pain, as ...
Source: BMC Neurology - Category: Neurology Authors: Tags: Study protocol Source Type: research
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