Cancers, Vol. 11, Pages 811: Diffusion-Weighted Imaging Can Differentiate between Malignant and Benign Pleural Diseases

Cancers, Vol. 11, Pages 811: Diffusion-Weighted Imaging Can Differentiate between Malignant and Benign Pleural Diseases Cancers doi: 10.3390/cancers11060811 Authors: Katsuo Usuda Shun Iwai Aika Funasaki Atsushi Sekimura Nozomu Motono Munetaka Matoba Mariko Doai Sohsuke Yamada Yoshimichi Ueda Hidetaka Uramoto It is not clear whether magnetic resonance imaging (MRI) is useful for the assessment of pleural diseases. The aim of this study is to determine whether diffusion-weighted magnetic resonance imaging (DWI) can differentiate malignant pleural mesothelioma (MPM) from pleural dissemination of lung cancer, empyema or pleural effusion. The DWI was calibrated with the b value of 0 and 800 s/mm2. There were 11 MPMs (8 epithelioid and 3 biphasic), 10 pleural disseminations of lung cancer, 10 empyemas, and 12 pleural effusions. The apparent diffusion coefficient (ADC) of the pleural diseases was 1.22 ± 0.25 × 10−3 mm2/s in the MPMs, 1.31 ± 0.49 × 10−3 mm2/s in the pleural disseminations, 2.01 ± 0.45 × 10−3 mm2/s in the empyemas and 3.76 ± 0.62 × 10−3 mm2/s in the pleural effusions. The ADC of the MPMs and the pleural disseminations were significantly lower than the ADC of the empyemas and the pleural effusions. Concerning the diffusion pattern of DWI, all 11 MPMs showed strong continuous...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research