Androgen receptor plasticity and its implications for prostate cancer therapy

Drug resistance is a common occurrence in many diseases, ranging from antibiotic resistance in bacteria and antiviral resistance by HIV strains to drug resistance in cancer, where it represents an especially pressing and unresolved issue. Resistance arises in nearly all cancer types and across numerous different drug classes with distinct mechanisms of action [1]. This is due to the inherent nature of cancer, where populations of tumour cells are put under selective pressure; such that the cells that survive are those which evolve ways to avoid the immune system and chemotherapies.

Source: Cancer Treatment Reviews - June 10, 2019 Category: Cancer & Oncology Authors: Oliver Snow, Nada Lallous, Kriti Singh, Nathan Lack, Paul Rennie, Artem Cherkasov Tags: Complications of Treatment Source Type: research