The chronic blockade of angiotensin I-converting enzyme eliminates the sex differences of serum cytokine levels of spontaneously hypertensive rats.

In conclusion, serum ACE inhibition by enalapril eliminated the sexual dimorphisms of cytokine levels in SV animals, which suggests that enalapril exerts systemic anti-inflammatory and anti-hypertensive effects.
PMID: 23369979 [PubMed - as supplied by publisher]

Source: Braz J Med Biol Res - February 1, 2013 Category: Research Authors: Dalpiaz PL, Lamas AZ, Caliman IF, Medeiros AR, Abreu GR, Moyses MR, Andrade TU, Alves MF, Carmona AK, Bissoli NS Tags: Braz J Med Biol Res Source Type: research