An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo [Medical Sciences]

We describe 18F-MAPP, an activatable MPO activity radioprobe for positron emission tomography (PET) imaging. The activated radioprobe binds to proteins and accumulates at...

Source: Proceedings of the National Academy of Sciences - June 10, 2019 Category: Science Authors: Cuihua Wang, Edmund Keliher, Matthias W. G. Zeller, Gregory R. Wojtkiewicz, Aaron D. Aguirre, Leonard Buckbinder, Hye-Yeong Kim, Jianqing Chen, Kevin Maresca, Maaz S. Ahmed, Negin Jalali Motlagh, Matthias Nahrendorf, John W. Chen Tags: Biological Sciences Source Type: research