Predicting disease-causing variant combinations [Genetics]

We present here the Variant Combinations Pathogenicity Predictor (VarCoPP), a machine-learning approach that identifies pathogenic variant combinations in gene pairs (called...

Source: Proceedings of the National Academy of Sciences - June 10, 2019 Category: Science Authors: Sofia Papadimitriou, Andrea Gazzo, Nassim Versbraegen, Charlotte Nachtegael, Jan Aerts, Yves Moreau, Sonia Van Dooren, Ann Nowe, Guillaume Smits, Tom Lenaerts Tags: PNAS Plus Source Type: research