Multipotent fetal-derived Cdx2 cells from placenta regenerate the heart [Cell Biology]

The extremely limited regenerative potential of adult mammalian hearts has prompted the need for novel cell-based therapies that can restore contractile function in heart disease. We have previously shown the regenerative potential of mixed fetal cells that were naturally found migrating to the injured maternal heart. Exploiting this intrinsic mechanism...

Source: Proceedings of the National Academy of Sciences - June 10, 2019 Category: Science Authors: Sangeetha Vadakke-Madathil, Gina LaRocca, Koen Raedschelders, Jesse Yoon, Sarah J. Parker, Joseph Tripodi, Vesna Najfeld, Jennifer E. Van Eyk, Hina W. Chaudhry Tags: PNAS Plus Source Type: research