A Rare Presentation Of Penile Keloids After Traditional Circumcision: Case Report
ConclusionThis case highlights one of the more serious complications of circumcision. Although penile keloids are rare, the techniques involved in traditional circumcision potentially predispose to keloid formation in a genetically prone population.
In conclusion, there was a great association between IL-6 572 gene polymorphism and its serum level in patients with keloid specifically who have family history. PMID: 31304905 [PubMed - in process]
Conclusions According to our results, “excision + radiation” had significantly better outcomes than excision alone. “Excision + pressure” had better outcomes than excision + any other treatment modality, and excision + nonradiation adjuvant therapies were also better than “excision only,” although these findings did not reach statistical significance.
Condition: Keloid Scar Intervention: Device: Soliton's Acoustic Scar Reduction (SAR) Sponsors: Soliton; Emergent Clinical Consulting, LLC Not yet recruiting
Publication date: Available online 6 July 2019Source: Life SciencesAuthor(s): Yangang Zhang, Chuantao Cheng, Shuang Wang, Meifeng Xu, Dewu Zhang, Weihui ZengAbstractKeloid is characterized by overactive fibroblasts. Forkhead box M1 (FOXM1) is transcription factor that plays important roles in the progression of fibrosis. However, the role of FOXM1 in keloid has not been elucidated. In the present study, we examined the expression levels of FOXM1 in clinical keloid tissue specimens and primary keloid fibroblasts (KFs). The results showed that FOXM1 levels were significantly increased in both keloid tissues and KFs. To furth...
Conclusions: The authors conclude that changes in human position are strongly correlated with mechanical loading of the predilection sites, which leads to increased mechanical strain in the peripheral tissue surrounding keloids. Furthermore, increased mechanical strain in the peripheral tissue, which is the site of keloid progression, was correlated with aberrant expression of caveolin-1/ROCK signaling pathway. These findings suggest a novel mechanism for keloid progression.
No abstract available
Conclusion: Review of the literature revealed a myriad of options for the treatment of different scar types. Although there is not vast evidence in the literature in regard to combination treatments, these are becoming more popular, and it is the author’s opinion that combination treatments yield better overall results. J Drugs Dermatol. 2019;18(6):550-555. PMID: 31251547 [PubMed - as supplied by publisher]
AbstractMost of the widely used scales to evaluate scars are subjective relying on clinical observations. There is a growing need to find out a noninvasive objective tool for this purpose. The study is aimed at evaluating the value of the high-resolution ultrasound in the assessment of the scars when compared with a clinical evaluation scoring system, the Vancouver Scar Scale (VSS). The study included 22 patients with hypertrophic scars or keloids. At baseline, scars were assessed using the Vancouver Scar Scale and high-resolution ultrasound (13-MHz probe). Patients received three Nd:YAG laser sessions (100 J/cm2 flu...
One of the first-line options to treat keloid scars is corticosteroid injection after excision of the existing scar. A thorough literature search has shown a lack of research on the injection of corticosteroid...