Medical News Today: Undetected diabetes may double risk of heart attack, periodontitis

New research finds a link between undetected blood sugar disorders and a heightened risk of myocardial infarction — or heart attack — and periodontitis.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Dentistry Source Type: news

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The objective of this study was to investigate the vulnerability of hearts with aging, LVH, diabetes, and pregnancy to ischemic insult and their response to pacing postconditioning- (PPC-) induced heart protection. Methods: Hearts isolated from aged, spontaneously hypertensive and diabetic male and female rats and hearts from pregnant female rats (n=8 per group) were subjected to coronary occlusion followed by reperfusion using a modified Langendorff system. Hemodynamics data were computed digitally, and cardiac damage was accessed by measurements of infarct size and cardiac enzyme release. Results: There were no...
Source: Cardiology Research and Practice - Category: Cardiology Authors: Tags: Cardiol Res Pract Source Type: research
FRIDAY, June 14, 2019 -- Undetected dysglycemia is associated with both myocardial infarction (MI) and periodontitis (PD), according to a study published online June 10 in Diabetes Care. Anna Norhammar, M.D., from the Karolinska Institutet in...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Authors: Tanner C, Wang G, Liu N, Andrikopoulos S, Zajac JD, Ekinci EI Abstract ■Metformin is recommended as first-line therapy for type 2 diabetes because of its safety, low cost and potential cardiovascular benefits. ■The use of metformin was previously restricted in people with chronic kidney disease (CKD) - a condition that commonly coexists with diabetes - due to concerns over drug accumulation and metformin-associated lactic acidosis. ■There are limited data from observational studies and small randomised controlled trials to suggest that metformin, independent of its antihyperglycaemic effects, may be ...
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
CONCLUSIONS: A novel risk score incorporating 8 readily available clinical and angiographic variables had high discrimination for 30-day death after PCI across a wide range of clinical scenarios. PMID: 31186218 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
CONCLUSION: Absorb BVS for treatment of anatomically low-risk patients with DM show acceptable safety and efficacy outcomes at 1 year. If these promising results are confirmed after a longer follow-up period, new-generation bioresorbable scaffolds combined with refinement of implantation techniques might open new horizons for CAD treatment in DM patients. PMID: 31197750 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - Category: Cardiology Authors: Tags: Neth Heart J Source Type: research
New research, published inDiabetes Care, indicates that undetected diabetes greatly increases the risk of severe gum disease or heart attack.Medical News Today
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
CONCLUSION: Thirty days post PCI, IC tirofiban was more efficient in ameliorating blood flow in the coronary arteries and myocardial tissue perfusion in DM patients after STEMI despite bleeding events, and MACE rates showed no significant difference between the groups. The IC group showed better improvement in LVEF. PMID: 31194213 [PubMed - as supplied by publisher]
Source: Cardiovascular Journal of Africa - Category: Cardiology Authors: Tags: Cardiovasc J Afr Source Type: research
Conclusions The study results confirmed the excellent clinical performance of the Orsiro drug-eluting stents at 18 months in the whole all-comer population and in the prespecified high-risk subgroups.
Source: Journal of Cardiovascular Medicine - Category: Cardiology Tags: Research articles: Interventional cardiology. Coronary artery disease Source Type: research
Study finds calcium deposits are triggered by molecule produced by damaged cellsThe mysterious mechanism behind the hardening of arteries may have been solved, researchers have revealed, in a study that also suggests the first potential preventive drug for the condition linked to heart attack, dementia and stroke.Arteries harden as calcium becomes deposited in the elastic walls of the vessels, a process that happens as we age and is exacerbated for patients with diabetes or kidney disease. Stiffening can also occur as calcium becomes deposited in fatty plaques in the arteries – a condition called atherosclerosis.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Medical research Science Heart attack Society Dementia Stroke UK news Source Type: news
Publication date: Available online 9 June 2019Source: The LancetAuthor(s): Hertzel C Gerstein, Helen M Colhoun, Gilles R Dagenais, Rafael Diaz, Mark Lakshmanan, Prem Pais, Jeffrey Probstfield, Fady T Botros, Matthew C Riddle, Lars Rydén, Denis Xavier, Charles Messan Atisso, Leanne Dyal, Stephanie Hall, Purnima Rao-Melacini, Gloria Wong, Alvaro Avezum, Jan Basile, Namsik Chung, Ignacio CongetSummaryBackgroundTwo glucagon-like peptide-1 (GLP-1) receptor agonists reduced renal outcomes in people with type 2 diabetes at risk for cardiovascular disease. We assessed the long-term effect of the GLP-1 receptor agonist dulag...
Source: The Lancet - Category: General Medicine Source Type: research
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