Gene Test Might Someday Gauge Your Heart Attack Risk

TUESDAY, June 11, 2019 -- Can a DNA test predict a person's future heart health? Perhaps, researchers say. A team of Canadian researchers found that by analyzing a person's entire genome, it might be possible to predict their future heart disease...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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The objective of this study was to investigate the vulnerability of hearts with aging, LVH, diabetes, and pregnancy to ischemic insult and their response to pacing postconditioning- (PPC-) induced heart protection. Methods: Hearts isolated from aged, spontaneously hypertensive and diabetic male and female rats and hearts from pregnant female rats (n=8 per group) were subjected to coronary occlusion followed by reperfusion using a modified Langendorff system. Hemodynamics data were computed digitally, and cardiac damage was accessed by measurements of infarct size and cardiac enzyme release. Results: There were no...
Source: Cardiology Research and Practice - Category: Cardiology Authors: Tags: Cardiol Res Pract Source Type: research
(Natural News) Even the slightest brush with high blood pressure can be enough to scare many people into taking blood pressure medication. After all, high blood pressure can lead to heart disease and raise your risk of heart attack or stroke. However, researchers have found an even better way to get your blood pressure under...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
ConclusionTreatment with low dose colchicine was safe and well tolerated, but was not associated with a significantly increased likelihood of achieving a CRP level
Source: American Heart Journal - Category: Cardiology Source Type: research
ConclusionAs a novel inflammation-based risk score, the CRP/albumin ratio may be an easily accessible marker for assessment of stent restenosis risk.ResumoObjetivoA reestenose de stent permanece como um desafio clínico em doentes com cardiopatia isquémica. A reestenose de stent está associada a intervenções coronárias recorrentes bem como a aumento de internamentos e de custos médicos. A inflamação tem um papel significativo. Embora a associação entre reestenose de stent e o aumento dos níveis de proteína C-reativa (PCR) e a diminui&...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
Cardiovascular diseases remain the top global killer, with nearly 80% of related mortalities occurring in developing countries. Over half of cardiovascular diseases ’ mortality is due to coronary heart disease,...
Source: BMC Cardiovascular Disorders - Category: Cardiology Authors: Tags: Research article Source Type: research
New research, published inDiabetes Care, indicates that undetected diabetes greatly increases the risk of severe gum disease or heart attack.Medical News Today
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Conclusions: Significant differences in PROs across IHD subgroups were observed and determinants for poor outcomes suggested. Results may guide differentiated care initiatives and resource allocation for preventative strategies.
Source: Journal of Cardiovascular Nursing - Category: Nursing Tags: Feature Article/Online Only Source Type: research
Abstract Circulating microRNAs (miRNAs) are potential biomarkers for cardiovascular diseases. Our study aimed to determine whether miR-22-5p, miR-132-5p, and miR-150-3p represent novel biomarkers for acute myocardial infarction (AMI). Plasma samples were isolated from 35 AMI patients and 55 matched controls. Total RNA was extracted, and quantitative real-time PCR and ELISA were performed to investigate the expressions of miRNAs and cardiac troponin I (cTnI), respectively. We found that plasma levels of miR-22-5p and miR-150-3p were significantly higher during the early stage of AMI and their expression levels peak...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
AbstractPurpose of ReviewThe purpose of this paper is to review current and new modalities to image key biological processes in ischemic heart disease and after myocardial infarction non-invasively.Recent FindingsNew imaging targets have been developed to detect and quantify myocardial damage after ischemia. Although positron emission tomography (PET) has been leading the development of new probes in the past, continuous improvements of magnetic resonance imaging (MRI) together with the development of new novel MRI contrast agents opens new research avenues including the combination of both PET and MRI to obtain anatomic, ...
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research
Publication date: Available online 10 June 2019Source: Life SciencesAuthor(s): Zhengbin Zhang, Yanzhen Tan, Liwen Zhu, Bing Zhang, Pan Feng, Erhe Gao, Chennian Xu, Xiaoming Wang, Wei Yi, Yang SunAbstractAimsSeveral adipokines have been proven to improve the therapeutic efficacy of mesenchymal stromal cells (MSCs) when used to treat ischemic heart disease. Asprosin (ASP) is a newly-discovered adipokine. ASP might also predict the severity of coronary pathology. We investigated the role of ASP on MSCs and the effects of ASP-pretreated MSCs on myocardial infarction (MI).Main methodsMSCs were labelled with a lentivirus carryin...
Source: Life Sciences - Category: Biology Source Type: research
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