Randomized Placebo-Controlled Trial Evaluating the Ophthalmic Safety of Single-Dose Tafenoquine in Healthy Volunteers

ConclusionThere was no evidence of any pharmacodynamic effect of 300-mg single-dose tafenoquine on the retina or any short-term clinically relevant effects on ophthalmic safety. This clinical trial is registered with ClinicalTrials.gov (identifier: NCT02658435).
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research

Related Links:

Conclusion: The overall performance of the kit was below the WHO standard. Further study on a large sample size is recommended to be carried out in the study area to use the test kit instead of microscopy for malaria diagnosis. Providing training on quality malaria laboratory diagnosis and availing necessary supplies for malaria diagnosis shall also be considered. PMID: 32963553 [PubMed]
Source: Journal of Tropical Medicine - Category: Tropical Medicine Tags: J Trop Med Source Type: research
[Ethiopian Herald] ADDIS ABABA- Gambela State Health Bureau announced that following the rainy season that ushered favorable condition for the reproduction of misquotes people are being infected with the disease of Malaria.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Publication date: Available online 21 September 2020Source: PhytomedicineAuthor(s): Jérôme Munyangi, Lucile Cornet-Vernet, Michel Idumbo, Chen Lu, Pierre Lutgen, Christian Perronne, Nadège Ngombe, Jacques Bianga, Bavon Mupenda, Paul Lalukala, Guy Mergeai, Dieudonné Mumba, Melissa Towler, Pamela Weathers
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
[Nation] The war against malaria just received a shot in the arm after new research should the potential a rare blood group could hold.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
[Malaria Consortium] When COVID-19 was declared a pandemic by WHO in March 2020, governments and organisations involved in the prevention and control of malaria had a choice to make - divert their attention from the diagnosis, control and prevention of malaria to that of COVID-19, or leverage the existing surveillance systems to fight both as effectively as possible.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
We present advances in modeling techniques that have led to fundamental disease discoveries and impacted clinical translation.Recent FindingsCombining mechanistic models and machine learning algorithms has led to improvements in the treatment ofShigella and tuberculosis through the development of novel compounds. Modeling of the epidemic dynamics of malaria at the within-host and between-host level has afforded the development of more effective vaccination and antimalarial therapies. Similarly, in-host and host-host models have supported the development of new HIV treatment modalities and an improved understanding of the i...
Source: Current Pathobiology Reports - Category: Laboratory Medicine Source Type: research
Publication date: 22 September 2020Source: Cell Reports, Volume 32, Issue 12Author(s): Guoyue Xu, Rebekah van Bruggen, Christian O. Gualtieri, Neda Moradin, Adrien Fois, Diane Vallerand, Mariana De Sa Tavares Russo, Angelia Bassenden, Wenyun Lu, Mifong Tam, Sylvie Lesage, Hélène Girouard, Daina Zofija Avizonis, Geneviève Deblois, Josef T. Prchal, Mary Stevenson, Albert Berghuis, Tom Muir, Joshua Rabinowitz, Silvia M. Vidal
Source: Cell Reports - Category: Cytology Source Type: research
Surveillance of low-density infections and of exposure to vectors is crucial to understand where malaria elimination might be feasible, and where the risk of outbreaks is high. Archived rapid diagnostic tests ...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
uraffour Elisabeth Fichet-Calvet Lassa fever is a rodent-borne disease caused by Lassa virus (LASV). It causes fever, dizziness, vertigo, fatigue, coughing, diarrhea, internal bleeding and facial edema. The disease has been known in Guinea since 1960 but only anectodical acute cases have been reported to date. In January 2019, a 35-year-old man, a wood merchant from Kissidougou, Forest Guinea, presented himself at several health centers with persistent fever, frequent vomiting and joint pain. He was repeatedly treated for severe malaria, and died three weeks later in Mamou regional hospital. Differential diagnosis id...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Researchers at the Harvard Wyss Institute have developed a rapid, inexpensive, and very sensitive malaria test that harnesses the power of CRISPR. The new technique does not require complicated sample preparation or processing, and it could allow for...
Source: Medgadget - Category: Medical Devices Authors: Tags: Diagnostics Public Health Source Type: blogs
More News: Clinical Trials | Drugs & Pharmacology | Malaria | Opthalmology | Study | Vitamin A