Fatty Acids Corrupt Neutrophils in Cancer

Publication date: 10 June 2019Source: Cancer Cell, Volume 35, Issue 6Author(s): Max D. Wellenstein, Karin E. de VisserUnderstanding how tumors escape from immune attack may offer novel therapeutic opportunities. Veglia et al. (2019) demonstrate in Nature that fatty acid transport protein 2 (FATP2) endows neutrophils with immunosuppressive capabilities that promote cancer growth. This receptor can be targeted to unleash anti-tumor immunity and to potentiate immune checkpoint blockade.
Source: Cancer Cell - Category: Cancer & Oncology Source Type: research