Ascending Lipopolysaccharide-Induced Intrauterine Inflammation in Near-Term Rabbits Leading to Newborn Neurobehavioral Deficits

Conclusions: This is the first study using an ascending LPS-induced intrauterine inflammation model in rabbits, showing mostly transient hypertonia and mainly locomotor deficits in the kits. Not all proinflammatory cytokines are increased in the fetal brain following LPS administration. Changes in key tetrahydro ­biopterin biosynthetic enzymes possibly indicate different effects of the inflammatory insult.Dev Neurosci
Source: Developmental Neuroscience - Category: Neuroscience Source Type: research

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Conclusions: In vivo exposure to remifentanil exerts a beneficial effect against excitotoxicity on the developing mouse brain, which is associated with a reduction in the size of ibotenate-induced brain lesion as well as prevention of some behavioral deficits in young mice. The long-term effect of neonatal exposure to remifentanil should be investigated. Introduction The potential neurotoxicity of anesthetics in the perinatal period prompted the US Food and Drug Administration (FDA) to release a drug safety communication warning in 2016 that stated, “repeated or lengthy use of general anesthetics or sedation ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Marjon E. Feenstra1†, Mirthe H. Schoots2†, Torsten Plösch1, Jelmer R. Prins1, Sicco A. Scherjon1, Albertus Timmer2, Harry van Goor2 and Sanne J. Gordijn1* 1Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands 2Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands Objective: Management of late fetal growth restriction (FGR) is limited to adequate fetal monitoring and optimal timing of delivery. The Disproportionate Intrauterine Growth Intervention ...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
CONCLUSIONS: Elective induction of labor in uncomplicated singleton pregnancies from 39 weeks' gestation is not associated with maternal or perinatal complications and may reduce the risk of Cesarean section, hypertensive disease of pregnancy and need for neonatal respiratory support. This article is protected by copyright. All rights reserved. PMID: 30298532 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
After years of fertility struggles, loss and pain, a Canadian family found renewed hope through surrogacy. On Jan. 22, Kate Austin-Rivas and Didier Rivas welcomed their daughter Scarlett Ryan via surrogate. Birth photographer Ashley Marston was present to capture this powerful moment of joy -- which came after many years of darkness. For Kate and Didier, the journey to parenthood has been filled with tragedy. After suffering multiple miscarriages, the couple welcomed their daughter Elle in 2010. Two years later, Kate delivered a stillborn baby girl, whom they named Katelyn. After another miscarriage, t...
Source: Science - The Huffington Post - Category: Science Source Type: news
ConclusionsTraining programs for improved interpretation of FHR tracing and appropriate TOID are required to prevent NE‐CP among healthy and mature fetuses in Japan.
Source: Journal of Obstetrics and Gynaecology Research - Category: OBGYN Authors: Tags: Original Article Source Type: research
(CNN) – If you are a woman and you and your partner are planning a pregnancy, it’s important to have your blood sugar levels in control before conceiving. When a woman becomes pregnant, a glucose screening test is done. If those results reveal elevated blood glucose levels, a glucose tolerance test can help determine if both mom and baby could be at risk. Dr. Sharon Bergquist, Assistant Professor of Medicine at Emory University, said: If a woman develops gestational diabetes throughout their pregnancy or has diabetes going into a pregnancy, that high blood sugar, if it’s not controlled, can lead to compli...
Source: Cord Blood News - Category: Perinatology & Neonatology Authors: Tags: babies brain development Cord Blood medical research parents pregnancy stem cells Uncategorized affordable cord blood banking blood sugar cerebral palsy cord blood banking fees cord blood treatment for Leukemia cord clamping du Source Type: blogs
    by Cari Nierenberg, Live Science Contributor Being pregnant can be a tiring experience for a woman’s body. Both the physical discomforts of pregnancy as well as the emotional stress of this major life change can cause sleep problems and keep a mother-to-be awake at night. Feeling exhausted is a common complaint during the first and third trimesters. But women might be caught off guard by how worn out they feel in the early months of pregnancy. “A lot of women are totally surprised by how fatigued they feel during the first trimester,” said Kathy Lee, a professor of nursing at the University...
Source: Cord Blood News - Category: Perinatology & Neonatology Authors: Tags: babies brain development Cord Blood medical research parents pregnancy stem cells Uncategorized affordable cord blood banking cerebral palsy cord blood banking fees cord blood treatment for Leukemia cord clamping due dates heal Source Type: blogs
During pregnancy, it is important to get the proper nutrients to foster healthy fetal development. You may be tempted to take a multivitamin in addition to other supplements. However, vitamin overdose can occur when an individual takes more than the recommended daily amount of a vitamin. This can result when taking more than one multivitamin, or when taking individual vitamins in addition to a multivitamin. While any vitamin can be toxic if taken in large amounts, calcium and iron pose the greatest toxic risks when taken in excess. Taking a multivitamin during pregnancy is important, although it is best to talk with your d...
Source: Cord Blood News - Category: Perinatology & Neonatology Authors: Tags: babies brain development Cord Blood medical research parents pregnancy affordable cord blood banking breast feeding C-section caesarian cerebral palsy due dates healthy pregnancy new baby parenting vaginal birth after caesari Source Type: blogs
When I discovered I was pregnant with twins, my husband and I burst into tears of joy, followed by utter panic. Two of them? I soon realized that carrying multiples meant I would likely wind up having a C-section (a typical procedure for twin pregnancies). However, the idea of a potentially long and painful labor and delivery—times two—was scary, so I was relieved when my obstetrician suggested we go with a C-section. But the experience wasn’t all spinal taps and roses: In addition to a long and painful recovery, I was left with a surprising post-surgery souvenir: a brand new pooch that hovers right above...
Source: Cord Blood News - Category: Perinatology & Neonatology Authors: Tags: babies blood disorder brain development Cord Blood medical research parents pregnancy stem cells affordable cord blood banking breast feeding C-section caesarian cerebral palsy due dates healthy pregnancy new baby parenting Source Type: blogs
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