Dosimetric effect of rotational setup errors in single-isocenter volumetric-modulated arc therapy of multiple brain metastases

Conclusion: Our results indicate that correcting rotational uncertainties is critical in single-isocenter, multi-target SRS. For rotational deviations, radial distance of the target from isocenter along the respective axis has a strong influence on target coverage. For rotational setup deviation at a given radial distance larger targets tend to have lesser geometric miss compared to smaller targets. Mathematical model for spherical targets can be used to estimate V95 for given rotational errors.

Source: Journal of Medical Physics - June 10, 2019 Category: Physics Authors: Kasirajan Tamil Selvan Ganesan Padma Murugesan Kesavan Revathy N Arunai Nambi Raj K Senthilnathan P Ramesh Babu Source Type: research