Ultrasonographic assessment of organs other than the heart in patients with heart failure

AbstractThe number of patients with heart failure has been dramatically increasing in Japan in association with aging of the society. This phenomenon is referred to as a heart failure pandemic. The fundamental origin of heart failure is cardiac dysfunction. Echocardiography is widely used to assess cardiac function, as well as to diagnose heart diseases that cause cardiac dysfunction. However, the severity of heart failure is not necessarily correlated with that of cardiac dysfunction. This is partly explained by the fact that heart failure induces dysfunction of organs other than the heart through hemodynamic deterioration and neurohumoral changes. In addition, one of the characteristics of patients with heart failure, particularly elderly patients, is the presence of numerous comorbidities. Symptoms of heart failure are not specific, and assessment of cardiac function, particularly left ventricular diastolic function, has not been established. Thus, ultrasonographic assessment of organs other than the heart helps the diagnosis of heart failure, assessment of the severity of heart failure, and development of our understanding of the pathophysiology in each patient. This review summarizes current knowledge about the usefulness of ultrasonographic assessment of organs other than the heart in heart failure.
Source: Journal of Medical Ultrasonics - Category: Radiology Source Type: research

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The rapid global increase in the number of patients with heart failure (HF) has reached an “HF pandemic” level. Worldwide, approximately 26 million patients are suffering from HF [1], with 5.1 million patients reported in the USA alone [2]. More than 1 million patients are hospitalized for HF in the USA and Europe annually [1]. In this “HF pandemic” situation, the rates of mortali ty and re-hospitalization remain high and increases annually despite the development of new treatments and approaches [3].
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
Heart failure is a worldwide pandemic with an unacceptable high level of morbidity and mortality. Understanding the different pathophysiological mechanisms will contribute to prevention and individualized therapy of heart failure. We established mouse models for ischemic cardiomyopathy (ICM) and dilated cardiomyopathy (DCM) by inducing myocardial infarction and Coxsackievirus B3 infection respectively. Isobaric tags for relative and absolute quantitation and liquid chromatography coupled with tandem mass spectrometry technology was used to identify the protein expression profiles in control and failing hearts. A total of 1...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Heart failure (HF) is a pandemic, chronic degenerative disease estimated to affect 38 million people worldwide, a number expected to increase with the ageing of the population.1 As a syndrome, it is associated with high mortality and morbidity, and consistently requires increasing resources.
Source: Radcliffe Cardiology - Category: Cardiology Authors: Source Type: research
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Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
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