Characterization of internalin genes in Listeria monocytogenes from food and humans, and their association with the invasion of Caco-2 cells

ConclusionOverall, the study has revealed the reduced ability ofL. monocytogenes to invade human intestinal epithelial cells in vitro was linked to the presence of PMSC mutations ininlA. Isolates with PMSC mutations shared the same genomic characteristics indicating the genetic basis on the potential virulence ofL. monocytogenes invasion.
Source: Gut Pathogens - Category: Microbiology Source Type: research