Vitreoretinal lymphoma followed by systemic diffuse large B cell lymphoma

AbstractVitreoretinal lymphoma as the presenting diagnosis in association with a systemic lymphoma without central nervous system involvement is exceedingly rare, and the classification of this condition is not well-established. Here, we describe a patient with intermittent blurry vision in the left eye for 2  years in the setting of a recent incidental diagnosis of diffuse large B cell lymphoma from an axillary lymph node biopsy. The diagnosis of panuveitis with an extensive exudative retinal detachment was made. The patient was treated with pars plana vitrectomy as well as systemic chemotherapy, intr athecal methotrexate, intravitreal methotrexate, and intravitreal rituximab with good post-operative outcomes.
Source: Journal of Ophthalmic Inflammation and Infection - Category: Opthalmology Source Type: research